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Common Medications for BPH

If you’re struggling with symptoms of BPH and considering medications to manage your symptoms, you’re in the right place. There are a few different types of BPH medications, and they work in different ways.

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Alpha blockers

Alpha blockers work by relaxing the muscles of the urinary tract, bladder and prostate to allow urine to flow more freely.1 While men may see an improvement in their BPH symptoms in a few days with alpha blockers, it is also possible to experience side effects such as dizziness and sexual dysfunction (ex. problems ejaculating).1,2 For an enlarged prostate, the common alpha blockers list of medications includes:1,2

• Alfuzosin (Uroxatral®)3

• Doxazosin (Cardura®)4

• Silodosin (Rapaflo®)5

• Tamsulosin (Flomax®, generic)6

• Terazosin (Hytrin®)

5-alpha reductase inhibitors

These types of medications work by blocking the change of the male hormone testosterone in your body into another hormone called DHT.1 This can help stop the growth of the prostate or can help reduce its size.1 However, since these medications affect your hormones, there can be some side effects such as a decreased sex drive or erectile dysfunction (trouble getting or maintaining an erection).1 Another consideration is that these drugs can take time to show symptom relief – anywhere from three to six months.1 5-alpha reductase inhibitors commonly prescribed for BPH include:1,2

• Finasteride (Proscar®)8

• Dutasteride (Avodart®)9

Phosphodiesterase-5 inhibitors

Tadalafil (Cialis®) is a phosphodiesterase-5 inhibitor that is primarily prescribed as a medication for erectile dysfunction. Tadalafil is also prescribed for BPH symptoms and works by relaxing the muscles of the bladder and prostate, which can help ease the flow of urine. One consideration to keep in mind for such medications is that they can lower blood pressure.1,2

Combination therapy

Depending on your treatment needs, your doctor may suggest using one or more of these medications in combination. Combination therapy can help manage BPH symptoms, and sometimes can counter the negative side effects of BPH medications..1,2

Although medications can help manage the symptoms of BPH, not all medications reduce the extra prostate tissue causing BPH.1,2 And relief doesn’t have to come with the potential side effects of medications.

Treat the BPH

Rezūm™ Water Vapor Therapy is a minimally invasive treatment for men 50 years or older that’s been proven to remove prostate tissue and provide BPH symptom relief out to 5 years after treatment, while preserving sexual function out to five years after the treatment.10

Medications are often prescribed as a first-line therapy for BPH – in other words, as the first treatment option before trying other solutions. But you don’t have to settle for meds before finding treatment. Based on data from 947 patients, 86% of BPH patients receive Rezūm as a first-line therapy or as an alternative to BPH medication.11*

If you’re experiencing BPH, talk to your doctor about your treatment options.

* Data collected by or on behalf of BSC. Data on file.

Most patients report relatively minor discomfort during the Rezūm procedure. Potential risks associated with Rezūm Water Vapor Therapy include but are not limited to painful or frequent urination, blood in the urine or semen, decrease in ejaculatory volume, urinary tract infection (UTI), inability to urinate or completely empty the bladder, and urgent need to urinate. During healing, symptoms may continue or worsen. Most men require a catheter for several days post-procedure.13,15 A complete list of risk information can be found here.

Find a Doctor

Use our Doctor Finder to get in direct contact with urologists who specialize in using Rezūm Water Vapor Therapy to treat BPH. 

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Read more about medications for BPH

References:

  1. Your benign prostatic hyperplasia medication: When to consider a change. Harvard Health Publishing. https://www.health.harvard.edu/blog/your-benign-prostatic-hyperplasia-medication-when-to-consider-a-change-2009031134. Accessed April 25, 2022. 
  2. Lerner LB, McVary, KT, Barry MJ, et al. Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA Guideline part I, initial work-up and medical management. J Urol. 2021 Oct;206(4):806-17. 
  3. Uroxatral Prescribing Information. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021287s013lbl.pdf. Accessed April 25, 2022. 
  4. Cardura Label. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019668s021lbl.pdf. Accessed April 25, 2022. 
  5. Rapaflo Prescribing Information. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022206s012lbl.pdf. Accessed April 25, 2022. 
  6. Flomax Prescribing Information. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020579s026lbl.pdf. Accessed April 25, 2022. 
  7. Hytrin Label. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019057s022lbl.pdf. Accessed April 25, 2022. 
  8. Proscar Tablets Patient Information. Organon Global Inc. https://www.organon.com/product/usa/pi_circulars/p/proscar/proscar_ppi.pdf. Accessed April 26, 2022. 
  9. Avodart Consumer Medicine Information. GlaxoSmithKline plc. https://au.gsk.com/media/6268/avodart_cmi_au_009_approved.pdf. Accessed April 26, 2022. 
  10. McVary KT, Gittelman MC, Goldberg KA, et al. Final 5-year outcomes of the multicenter randomized sham-controlled trial of Rezūm water vapor thermal therapy for treatment of moderate-to-severe lower urinary tract symptoms secondary to benign prostatic hyperplasia. J Urol. 2021 Sep;206(3):715-24. 
  11. Data on file with Boston Scientific.  
  12. Mooney R, Goldberg K, Wong D, et al. Convective radio frequency thermal therapy for treatment of benign prostatic hyperplasia: single office experience with 255 patients over 4 years. Urol Pract. 2020 Jan;7(1):28-33. 

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